{"id":1040,"date":"2023-08-09T01:29:42","date_gmt":"2023-08-09T01:29:42","guid":{"rendered":"https:\/\/itm.nycu.edu.tw\/?page_id=1040"},"modified":"2023-08-09T02:27:39","modified_gmt":"2023-08-09T02:27:39","slug":"%e6%9e%97%e5%ae%a5%e6%88%90-%e5%8a%a9%e7%90%86%e6%95%99%e6%8e%88","status":"publish","type":"page","link":"https:\/\/itm.nycu.edu.tw\/?page_id=1040","title":{"rendered":"\u6797\u5ba5\u6210 \u52a9\u7406\u6559\u6388"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

\u3010\u7c21\u4ecb\u3011<\/h4>\n\n\n\n

\u672c\u5be6\u9a57\u5ba4\u904a\u8d70\u65bc\u6a5f\u5668\u5b78\u7fd2\u3001\u57fa\u56e0\u9ad4\u3001\u8207\u53e3\u8154\u91ab\u5b78\u7684\u4ea4\u754c\uff0c\u4f46\u57fa\u672c\u4e0a\u6211\u5011\u6bcf\u5929\u505a\u7684\u5c31\u662f\u628a\u5496\u5561\u8f49\u63db\u6210\u7a0b\u5f0f\u78bc \"\ud83d\ude03\"<\/p>\n\n\n\n

\u6211\u5011\u76f8\u4fe1\u751f\u7269\u5b78\u7684\u672c\u8cea\u662f\u300c\u5c0f\u300d\u7684\u79d1\u5b78\uff0c\u56e0\u6b64\u6211\u5011\u63a1\u884c\u8edf\u9ad4\u8a2d\u8a08\u7684\u654f\u6377\u958b\u767c\uff0c\u6574\u5408\u300c\u4e7e\u3001\u6fd5\u300d\u5be6\u9a57\uff0c\u6316 \u6398\u751f\u7269\u65b0\u77e5<\/p>\n\n\n\n

\u3010\u7814\u7a76\u65b9\u5411\u3011<\/h4>\n\n\n\n

\u53e3\u8154\u764c\u57fa\u56e0\u9ad4\u5b78\u3001\u7cbe\u6e96\u91ab\u7642\u3001\u53e3\u8154\u5fae\u751f\u7269\u83cc\u76f8<\/p>\n\n\n\n

\u3010\u5c08\u9577\u3011<\/h4>\n\n\n\n

\u751f\u7269\u8cc7\u8a0a\u3001\u6a5f\u5668\u5b78\u7fd2\u3001\u57fa\u56e0\u9ad4\u5b78\u3001\u5fae\u751f\u7269\u5b78\u3001\u907a\u50b3\u5b78<\/p>\n\n\n\n

\u3010\u5b78\u6b77\u3011<\/h4>\n\n\n\n
\u7562\u696d\u5b78\u6821<\/strong><\/td>\u570b\u5225<\/strong><\/td>\u4e3b\u4fee\u7cfb\u5225<\/strong><\/td>\u5b78\u4f4d<\/strong><\/td>\u7562\u696d\u5e74\u5ea6<\/strong><\/td><\/tr>
\u54e5\u502b\u6bd4\u4e9e\u5927\u5b78<\/td>\u7f8e\u570b<\/td>\u751f\u7269\u5b78\u7cfb<\/td>\u535a\u58eb<\/td>2018<\/td><\/tr>
\u570b\u7acb\u53f0\u7063\u5927\u5b78<\/td>\u53f0\u7063<\/td>\u5fae\u751f\u7269\u8207\u751f\u5316\u5b78\u7814\u7a76\u6240<\/td>\u78a9\u58eb<\/td>2010<\/td><\/tr>
\u570b\u7acb\u53f0\u7063\u5927\u5b78<\/td>\u53f0\u7063<\/td>\u7259\u91ab\u5b78\u7cfb<\/td>\u5b78\u58eb<\/td>2008<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u3010\u7d93\u6b77\u3011<\/strong><\/p>\n\n\n\n

\u670d\u52d9\u55ae\u4f4d<\/strong><\/td>\u670d\u52d9\u90e8\u9580<\/strong><\/td>\u8077\u7a31<\/strong><\/td>\u670d\u52d9\u671f\u9593<\/strong><\/td><\/tr>
\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78<\/td>\u7259\u91ab\u5b78\u7cfb<\/td>\u52a9\u7406\u6559\u6388<\/td>2021 \u2013 \u73fe\u4eca<\/td><\/tr>
LifeMine Therapeutics<\/td>\u8cc7\u6599\u79d1\u5b78\u90e8\u9580 \u2013 \u57fa\u56e0\u9ad4\u7d44<\/td>\u8cc7\u6df1\u8a08\u7b97\u751f\u7269\u5b78\u7814\u7a76\u54e1<\/td>2019 \u2013 2021<\/td><\/tr>
\u65b0\u82f1\u683c\u862d\u5be6\u9a57\u5ba4<\/td>\u7814\u7a76\u90e8\u9580<\/td>\u535a\u58eb\u5f8c\u7814\u7a76\u54e1<\/td>2018 \u2013 2019<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
\u8a08\u756b\u540d\u7a31<\/strong><\/td>\u64d4\u4efb\u5de5\u4f5c<\/strong><\/td>\u57f7\u884c\u671f\u9593<\/strong><\/td>\u55ae\u4f4d<\/strong><\/td><\/tr>
\u4ee5\u53ef\u89e3\u8b80\u4e4b\u6df1\u5ea6\u5b78\u7fd2\u89e3\u6790\u53e3\u8154\u4e0a\u76ae\u9c57\u72c0\u7d30\u80de\u764c\u4e4b\u57fa\u56e0\u9ad4<\/td>\u4e3b\u6301\u4eba<\/td>2022\/8\/1 \u2013 2025\/7\/31<\/td>\u570b\u79d1\u6703<\/td><\/tr>
\u53e3\u8154\u764c\u7cbe\u6e96\u91ab\u7642\u5148\u5c0e\u578b\u8a08\u756b<\/td>\u5354\u540c\u4e3b\u6301\u4eba<\/td>2022\/7\/1 \u2013 2022\/12\/31<\/td>\u885b\u798f\u90e8<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u96fb\u5b50\u90f5\u4ef6\uff1a<\/strong>ylin@nycu.edu.tw<\/a><\/p>\n\n\n\n

\u3010\u8457\u4f5c\u3011<\/strong><\/p>\n\n\n\n

    \n
  1. Tsai F-T, Wang D-H, Yang C-C, Lin Y-C<\/u><\/strong>, Huang L-J, Tsai W-Y, Li C-W, Hsu W-E, Tu H-F & Hsu M-L (2022) Locational effects on oral microbiota among long-term care patients. Journal of Oral Microbiology<\/em>, 14(1): 2033003.<\/li>\n\n\n\n
  2. *Yang W, *Lin Y-C<\/u><\/strong>, Johnson W, Dai N, Vaisvila R, Weigele PR, Lee Y-J, Corr\u00eaa IR Jr, Schildkraut I & Ettwiller L (2021) A Genome-Phenome Association study in native microbiomes identifies a mechanism for cytosine modification in DNA and RNA. eLife<\/em>, 10:e70021. *These authors contributed equally<\/li>\n\n\n\n
  3. Lee Y-J, Dai N, Muller SI, Guan C, Parker MJ, Fraser ME, Walsh SE, Sridar J, Mulholland A, Nayak K, Sun Z, Lin Y-C<\/u><\/strong>, Comb DG, Marks K, Gonzalez R, Dowling DP, Bandarian V, Saleh L, Corr\u00eaa IR Jr & Weigele PR (2021) Pathways of thymidine hypermodification. Nucleic Acids Research<\/em>.<\/li>\n\n\n\n
  4. Baum C, Lin Y-C<\/u><\/strong>, Fomenkov A, Anton BP, Chen L, Yan B, Evans TC, Roberts RJ, Tolonen AC, Ettwiller L (2021) Rapid identification of methylase specificity (RIMS-seq) jointly identifies methylated motifs and generates shotgun sequencing of bacterial genomes. Nucleic Acids Research<\/em>.<\/li>\n\n\n\n
  5. Wang B, Lin Y-C<\/u><\/strong>, Vasquez-Rifo A, Jo J, Price-Whelan A, McDonald ST, Brown LM, Sieben C, Dietrich LEP (2021) Pseudomonas aeruginosa PA14 produces R-bodies, extendable protein polymers with roles in host colonization and virulence. Nature Communications<\/em>, 12(1): 4613.<\/li>\n\n\n\n
  6. Chen J-L, Lin Y-C<\/u><\/strong>, Fu H-Y, Yang C-S (2019) The Blue-Green Sensory Rhodopsin SRM from Haloarcula marismortui<\/em> Attenuates Both Phototactic Responses Mediated by Sensory Rhodopsin I and II in Halobacterium salinarum<\/em>. Scientific Reports<\/em> 9: 5672.<\/li>\n\n\n\n
  7. Lin Y-C<\/u><\/strong>, Cornell W-C, Jo J, Price-Whelan A, Dietrich LEP (2018) The Pseudomonas aeruginosa<\/em> Complement of Lactate Dehydrogenases Enables Use of D- and L-Lactate and Metabolic Cross-Feeding. mBio<\/em> 9: e00961-18.<\/li>\n\n\n\n
  8. Lin Y-C<\/u><\/strong>, Sekedat MD, Cornell WC, Silva GM, Okegbe C, Price-Whelan A, Vogel C, Dietrich LEP (2018) Phenazines regulate Nap-dependent denitrification in Pseudomonas aeruginosa<\/em> biofilms. J. Bacteriol.<\/em>, JB.00031-18.<\/li>\n\n\n\n
  9. Fong JC, Rogers A, Michael AK, Parsley NC, Cornell W-C, Lin Y-C<\/u><\/strong>, Singh PK, Hartmann R, Drescher K, Vinogradov E, Dietrich LE, Partch CL, Yildiz FH (2017) Structural dynamics of RbmA governs plasticity of Vibrio cholerae<\/em> biofilms. eLife<\/em>, 6.<\/li>\n\n\n\n
  10. Choi PH, Jo J, Lin Y-C<\/u><\/strong>, Lin M-H, Chou C-Y, Dietrich LEP, Tong L (2016) A distinct holoenzyme organization for two-subunit pyruvate carboxylase. Nat. Commun.<\/em>, 7, 12713.<\/li>\n\n\n\n
  11. *Madsen JS, *Lin Y-C<\/u><\/strong>, *Squyres GR, Price-Whelan A, de Santiago Torio A, Song A, Cornell WC, S\u00f8rensen SJ, Xavier JB, Dietrich LEP (2015) Facultative control of matrix production optimizes competitive fitness in Pseudomonas aeruginosa<\/em> PA14 biofilm models. Appl. Environ. Microbiol.<\/em>, 81(24), 8414\u20138426. *These authors contributed equally<\/li>\n\n\n\n
  12. *H\u00f6lscher T, *Bartels B, *Lin Y-C<\/u><\/strong>, Gallegos-Monterrosa R, Price-Whelan A, Kolter R, Dietrich LEP, Kov\u00e1cs \u00c1T (2015) Motility, chemotaxis and aerotaxis contribute to competitiveness during bacterial pellicle biofilm development. J. Mol. Biol.<\/em> doi:10.1016\/j.jmb.2015.06.014 *These authors contributed equally<\/li>\n\n\n\n
  13. Lin Y-C<\/u><\/strong>, Fu H-Y, Yang C-S (2010) Phototaxis of Haloarcula marismortui<\/em> revealed through a novel microbial motion analysis algorithm. Photochem. Photobiol.<\/em> 86(5):1084-90.<\/li>\n\n\n\n
  14. Fu H-Y, Lin Y-C<\/u><\/strong>, Chang Y-N, Tseng H, Huang C-C, Liu K-C, Huang C-S, Su C-W, Weng RR, Lee Y-Y, Ng WV, Yang C-S (2010) A novel six-rhodopsin system in a single archaeon. J. Bacteriol. <\/em>192(22):5866-73.<\/li>\n<\/ol>\n\n\n\n

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